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The search yielded 12 studies in children and adolescents. Six of the twelve studies were from the United States. Eleven of the twelve studies used corticosteroids (10 trials) or NSAIDs (10 trials), liquid sarms. Of six trials using corticosteroids, six reported a statistically significant reduction in pain (all placebo-controlled studies) and five report no clinical benefit at all (one non-randomised, one controlled). In only two trials were the authors able to identify a statistically significant difference in pain scores at 12 weeks as a primary difference (one randomised controlled study) and in pain scores at 2 months after the 12-week treatment (four randomised controlled studies and one systematic review).
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